Secretin is an enzyme that is found in the pancreas and brain. It has been used in the treatment of ASD patients with some children responding in normalization of bowel function, behavior, speech and language. Secretin can be administered intravenously or as a daily nasal spray. 

The initial administration is IV and given in two monthly doses to determine its effectiveness. Secretin therapy is continued for six months. Patients have responded favorably in 50-85% of the trials. It is available in our office.